Free testosterone Lab Results explained

Free testosterone Lab Results explained

It’s critical to test both free testosterone levels and total T, along with other biomarkers like SHBG and estrogen. For example, if your total T levels are normal, research finds that symptoms of low testosterone can still exist. Total Testosterone levels, and in turn, free testosterone levels (3), start to decrease around age 30 by about 1 percent every year.

Ahead, men’s health experts answer the question, and share tips for supporting your T levels at any age. Total testosterone is a total measure of testosterone in the bloodstream — both free and bound. In dispelling common myths and misconceptions about testosterone, we aimed to provide clarity and information, fostering a better understanding of this hormone’s role in our bodies. The FDA currently advises against treating men with low testosterone caused only by aging.

If you’re looking to monitor your hormone regime, the Endocrine Society recommends testing total testosterone levels, alongside other hormones such as oestradiol and prolactin in trans women. Guidelines suggest monitoring hormone therapy every three months during the first year (that is, with each dose adjustment), then once or twice a year once the dose is stabilised [5–7]. That said, free or bioavailable testosterone measurements may be valuable if total testosterone levels don’t seem to align with the stage of transition [8], which may be due to raised SHBG levels. As infancy progresses, testosterone levels gradually increase, but still remain relatively low compared to later stages of life. The most significant changes in testosterone occur during puberty when levels surge to support the development of secondary sexual characteristics, such as facial hair growth, deepening voice, and muscle development.

Regular exercise, particularly strength training and high-intensity interval training (HIIT) can help boost testosterone production. A balanced diet rich in nutrients, including healthy fats, zinc, vitamin D, and supplements can also play a role in maintaining optimal hormone levels. Furthermore, certain medical conditions or medications may disrupt testosterone levels. Conditions like hypogonadism or obesity-related hormonal imbalances can lead to low testosterone, while medications like corticosteroids or opioids may also affect hormone production.

Albumin-bound testosterone has a weak bond and is, therefore, also classified as bioavailable testosterone. Testosterone testing (you can measure just total T or both total and free T) helps deliver results and sometimes is even used to diagnose health conditions such as erectile dysfunction or infertility. In 2025, clinics like AlphaMan, a men’s health center specializing in hormone optimization, are rethinking how does low testosterone affect males testosterone therapy fits into modern masculinity. Because when it comes to low testosterone, the stakes extend far beyond the gym. Even high-performing men balancing careers, families, and fitness can find themselves battling unexplained fatigue, diminished focus, low libido, and persistent sluggishness despite adequate rest. “Lifting also promotes muscle growth, reduces visceral fat, and further aids metabolism, which supports overall hormone health and well-being,” says Bailey.

A retrospective cohort study from the U.S. showed that testosterone replacement in men with hypogonadism significantly increased the risk of urolithiasis [25]. In another retrospective case‒control study from Taiwan, androgen deprivation in prostate cancer patients reduced the subsequent development of kidney stones [26]. These two retrospective studies suggest that testosterone might induce urinary stones. However, these results are limited because the data are derived from military service members and individuals with pathological conditions such as prostate cancer. Therefore, these retrospective results might lack some degree of generalizability beyond former service members and patients with prostate cancer. Some research suggests a potential link between higher exposure to endocrine-disrupting chemicals (EDCs) and lower testosterone levels, says Houman. This is likely because they can disrupt both endocrine function and healthy metabolism.

When it comes to normal free testosterone levels during adolescence and early adulthood, there are distinct ranges and variations to consider. Research conducted by Smith et al. (2019), published in the Journal of Endocrinology, sheds light on this topic. According to the Endocrine Society’s Clinical Practice Guidelines, the normal range for free testosterone in women is typically between 0.3 to 1.9 ng/dL (nanograms per deciliter). However, it’s important to note that these ranges may vary slightly depending on the specific laboratory and testing method used. Free testosterone and albumin-bound testosterone are called bioavailable testosterone.

The choice of treatment depends on the underlying cause of the imbalance, the severity of symptoms, and individual patient factors. The next section will explore how lifestyle choices can impact testosterone levels, emphasizing the role of personal health practices in managing and maintaining hormonal balance. It’s important to note that while these strategies can be effective, they may also carry risks. For instance, testosterone replacement therapy can potentially increase the risk of blood clots, sleep apnea, and prostate issues in men. Therefore, any medical intervention should be closely monitored by a healthcare professional.Implementing these strategies can help naturally boost % Free Testosterone, improving overall health and well-being.

A study published by Wu et al. (2020) in the Journal of Clinical Endocrinology & Metabolism provides insights into average testosterone levels during the 30s and 40s. When considering normal free testosterone levels during infancy and childhood, it’s essential to understand the baseline levels and the subsequent changes that occur during the growth and development process. A study published in the Journal of Clinical Endocrinology & Metabolism by Johnson et al. (2018) examined testosterone levels in newborns and infants. The study found that typical testosterone levels in newborns are relatively low, ranging from 0.1 to 0.8 ng/dL. Furthermore, high free testosterone levels in men can also have negative effects on the prostate gland.

Research conducted by Snyder et al. (2016), published in the New England Journal of Medicine, provides insights into expected testosterone levels in individuals aged 50 and beyond. Treatment for low free testosterone levels may include hormone replacement therapy (HRT). This involves the use of synthetic testosterone to supplement the body’s natural levels.